Prem S. Thapa-Chetri, Ph.D
- Senior Electron Microscopist
Contact Info
Lawrence
1200 Sunnyside Ave.
Lawrence, KS 66045
Biography —
Dr. Prem S. Thapa Chetri graduated with a Bachelor's degree in Electrical & Electronics Engineering from Bangladesh Institute of Technology in 1995. He received a master’s degree in Electrical Engineering in 2002 and earned his Ph.D. in Photonics in 2008 from Oklahoma State University. Dr. Thapa joined the University of Kansas in 2011 as a Microscopist. Prior to joining KU, he worked as a Post-doctoral Research Associate in the Department of Physics at Kansas State University from 2008-2011. Dr. Thapa also worked as a Lecturer in the Department of Electrical Engineering/ Institute of Engineering of Tribhuvan University, Nepal from 1996-1999.
Education —
Research —
Research Interests
Development and characterization of metallic, polymeric, and biomaterial nanostructures to apply as imaging probes for correlative optical and electron microscopy.
Application of Polymeric Nanoprobes as a measuring tool for subcellular forces and voltages.
Experimental techniques to investigate size effects at small scales, nanoscale fabrication methods, and sample preparation methods for electron microscopy, imaging and analysis, and study of interfaces.
High-resolution electron microscopy, X-ray Photoelectron Spectroscopy, and its application to biological, material, and geological sciences.
Application of focused ion beam system to micro and nanoscale structures or devices for specific research projects in scanning and transmission electron microscope.
Selected Publications —
United States Patent
- Rosa-Molinar, E., Das, S. R., Thapa-Chetri, P. S., Martinez-Rivera, N., and Xing, W., “Graphene Based Substrate for Imaging” (USPTO Prov. Patent App. Ser. No.62/ 778,140); filed: December 11, 2018.
Flanders, B. N., Talukdar, I., Ozturk, B., and Thapa, P. S. “Methods of Making an Electrochemical Nanowire assembly and Attaching Cells There to” (United States Patent: 8137526), 2012.
Book Chapter
- Ramanathan, A., Maheswari, R., Thapa, P. S., and Subramaniam, B. “Rapid Room Temperature Synthesis of Ce-MCM-48: An Active Catalyst for Trans-Stilbene Epoxidation with Tert-Butyl Hydroperoxide” in “Novel Materials for Catalysis and Fuels Processing”; J. Bravo-Suarez, J., Kidder, K. M., and Schwartz, V., ACS Symposium Series, Vol. 1132: American Physical Society; 2013: Chapter 8, pp213-228
Publications
2020
Stephens, K., Allgeier, A., Carlson, T., Douglas, J., Howe, L., Menning, C., Neuenswander, S., Sengupta, S., Thapa, P. and Ritter, J. “A Mechanistic Study of Polyol Hydrodeoxygenation over a Bifunctional Pt-WOx/TiO2 Catalyst” ACS Catalysis.
2019
- Al-Auda, Z., Al-Atabi, H., Li, X., Thapa, P. and Hohn, K. “Conversion of 5-Methyl-3-Heptanone to C8 Alkenes and Alkanes over Bifunctional Catalysts” Catalysts.
2018
- Yapa, A., S., Shrestha, T. B., Wendel, S. O., Kalubowilage, M., Jing, Y., Wang, H., Pyle, M., Basel, M., T., Malalasekera, A. P., Thapa, P., S., Troyer, D. L. and Bossmann, S. H. “Peptide Nanosponges Designed for the Delivery of Perilyl Alcohol to Glioma Cells” ACS Applied Biomaterials.
- Honghong, S., Thapa, P.S., Subramaniam, B., and Chaudhari, R.V. “Oxidation of Glucose using Mono and Bimetallic Catalysts in Base Free Conditions” Organic Process Research & Development
- Yapa, A., S., Wang, H., Wendel, S., O., Shrestha, T. B., Kariyawasam, N., L., L., Kalubowilage, M., Perera, A., S., Pyle, M., Basel, M., T., Malalasekera, A. P., Manawadu, H., C., Yu, J., Toledo, Y., Ortega, R., Thapa, P., S., Smith, P., E., Troyer, D. L. and Bossmann, S. H. “Peptide Nanosponges Designed for Rapid Uptake by Leukocytes and Neural Stem Cells” Royal Society of Chemistry Advances.
- Haider, A., Xu, L., Thapa, P., Keith, H. and Placidus, A. “Carbon Nanotube-Supported Catalysts Prepared by a Modified Photo-Fenton Process for Fischer-Tropsch Synthesis” Journal of ACS Catalysis
2017
- Thapa, P. S., Santiago-Robles, C. M., Martinez-Rivera, N., Torres-Vazquez, I., Joshi, V. N., Powell, R. D. and Rosa-Molinar, E. “Development and Characterization of Nanoparticles as Imaging Probes for Correlative Optical and Electron Microscopy” Proceedings of 17th IEEE International Conference on Nanotechnology.
- Liu, Q., Gong, M., Cook, B., Thapa, P., Ewing, D., Casper, M., Stramel, A., and Wu, J. “Oxygen Plasma Surface Activation of in situ Synthesized ZnO Nanoparticle Mesoporous Films for performance-enhanced Ultraviolet Photodetectors” Journal of Physica Status Solidi A- Applications and Materials Science.
- Jin, X., Yan, H., Zeng, C., Thapa, P. S., Subramaniam, B. and Chaudhari, R. V. “Phase Transformed PtFe Nanocomposites Show Enhanced Catalytic Performances in Oxidation of Glycerol to Tartronic Acid” Industrial & Engineering Chemistry Research.
- Abayaweera, G. S., Wang, H., Shrestha, T. B., Yu, J., Angle, K., Thapa, P., Malalasekera, A. P., Maurmann, L., Troyer, D. L. and Bossmann, S. H. “Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered Via a Magnetic Nanocarrier” Journal of Functional Biomaterials.
- Wang, H., Yapa, A., Kariyawasam, N., Shrestha, T. B., Wendel, S. O., Yu, J., Pyle, M., Basel, M. T., Malalasekera, A. P., Toledo, Y., Ortega, R., Thapa, P. S., Huang. H., Sun, S. X., Smith, P. E., Troyer, D. L. and Bossmann, S. H. “Rationally Designed Peptide Nanosponges for Cell-Based Cancer Therapy” Nanomedicine: Nanotechnology, Biology, and Medicine.
- Jin, X., Bobba, P., Reding, N., Song, Z., Thapa, P. S., Prasad, G., Subramaniam, B. and Chaudhari, R.V. “Kinetic modeling of carboxylation of propylene oxide to propylene carbonate using ion-exchange resin catalyst in a semi-batch slurry reactor” Chemical Engineering Science.
- Du, F., Jin, X., Yan. W., Zhao, M., Thapa, P. S. and Chaudhari, R. V. “Catalytic H2 auto-transfer amination of polyols to alkyl amines in one pot using supported Ru catalysts” Catalysis Today.
- Jin, X., Zeng, C., Yan, W., Zhao, M., Bobba, P., Shi, H., Thapa, P., Subramaniam, B. and Chaudhari, R. V. “Effects of Lattice Distortion Induced Electron Coupling in Exceptional Enhancement in the Activity of Bimetallic PtMn Nanocatalysts.” Applied Catalysis A.
- Basnet, G., Panta, K. R., Thapa, P. S., and Flanders, B. N. “Controlled Electrochemical Growth of Ultra-Long Gold Nanoribbons” Appl. Phys. Lett. 110.
2016
- Dou, J., Nguyen, L, Tong, X., Thapa, P. S., and Tao, F. “ Oxidation of Cyclohexene Catalyzed by Nanoporous Au(Ag) in Liquid Phase.” Journal of Catalysis Letters.
- Wahome, N., Cooper, A., Thapa, P., Chaudhari, S., Gao, F.P., Volkin, D.B., Middaugh, C.R, “Production of Well-Characterized Virus-like Particles in an Escherichia coli-Based Expression Platform for Preclinical Vaccine Assessments.” Methods Mol Biol.
- Jin, X., Thapa, P., Subramaniam, B. and Chaudhari, R. V. “Kinetic Modeling of Sorbitol Hydrogenolysis over Bimetallic RuRe/C Catalyst.” ACS Sustain. Chem.
- Jin, X., Zhao, M., Zeng, C., Yan, W., Song, Z., Thapa, P. S., Subramaniam, B. and Chaudhari, R. V. “Oxidation of Glycerol to Dicarboxylic Acids Using Cobalt Catalysts.” ACS Catalysis.
- Jin, X., Zhao, M., Vora, M., Shen, J., Zeng, C., Yan, W., Thapa, P. S., Subramaniam, B. and Chaudhari, R. V. “Synergistic Effects of Bimetallic PtPd/TiO2 Nanocatalysts in Oxidation of Glucose to Glucaric Acid: Structure Dependent Activity and Selectivity.” Industrial & Engineering Chemistry Research.
- Jin, X., Zhao, M., Yan, W., Zeng, C., Bobba, P., Thapa, P. S., Subramaniam, B. and Chaudhari, R. V. “ Anisotropic Growth of PtFe Nanoclusters Induced by Lattice-Mismatch: Efficient Catalysts for Oxidation of Biopolyols to Carboxylic Acid Derivatives.” Journal of Catalysis.
2015
- Jin, X., Subramaniam, B., Chaudhari, R. V. and Thapa, P. S. “Kinetic modeling of Pt/C catalyzed aqueous phase glycerol conversion with in situ formed hydrogen.” AIChE Journal.
- Jin, X., Shen, J., Yan, W., Zhao, M., Thapa, P. S., Subramaniam, B. and Chaudhari, R. V. “Sorbitol Hydrogenolysis over Hybrid Cu/CaO-Al2O3 Catalysts: Tunable Activity and Selectivity with Solid Base Incorporation.” ACS Catalysis.
- Telikepalli, S., Shinogle, H. E., Thapa, P. S., Kim, J. H., Deshpande, M., Jawa, V., Middaugh, R. C., Narhi, L. O., Joubert, M. K., and Volkin, D. B. “Physical Characterization and in Vitro Biological Impact of Highly Aggregated Antibodies Separated into Size Enriched Populations by FACS” Journal of Pharmaceutical Sciences.
- jin, X., Zhao, M., Shen, J., Yan, W., He, L., Thapa, P. S., Ren, S., Subramaniam, B. and Chaudhari, R. V. “Exceptional Performance of Bimetallic Pt1Cu3/TiO2 Nanocatalysts for Oxidation of Gluconic Acid and Glucose with O2 to Glucaric Acid.” Journal of Catalysis.
- Wang, H., Hodgson, J., Shrestha, T. B., Basel, G. M., Pyle, M., Toledo, Y., Thapa, P.S., Ikenberry, M., Hohn, K., Chikan, V., Troyer, D.L. and Bossmann, S. H.,“Hexagonal Magnetite Nanoprisms: Preparation, Characterization and Cellular Uptake” Journal of Material Chemistry B.
2014
- Ramanathan, A., Hongda, Z., Maheswari, R., Thapa, P., and Subramaniam, B. “A Comparative Study of Nb-Incorporated Cubic Mesoporous Silicates as Epoxidation Catalysts.” Industrial & Engineering Chemistry Research.
- Podaru, G., Ogden, S., Baxter, A., Shrestha, T., Ren, S., Thapa, P., Dani, R. K., Wang, H., Basel, M. T., Prakash, P., Bossmann, S. H., and Chikan, V. “Pulsed Magnetic Field Induced Fast Drug Release from Magneto Liposomes via Ultrasound Generation.” The Journal of Physical Chemistry.
- Ozan, K. S., Joshi, S. B., Thapa, P., Pheasey, N., Bullock, P. S., Bashiri, H., Siska, C. S., Kerwin, B. A., He, F., Volkin, D. B., and Middaugh, R. C. “Characterization of an Oncolytic Herpes Simplex Virus Drug Candidate” Journal of Pharmaceutical Sciences.
- Pandey, B., Cox, C., Thapa, P. S., and Ito Takashi, “Potentiometric Response Characteristics of Oxide-Coated Gallium Electrodes in Aqueous Solutions” Electrochim. Acta.
- Wang, H., Hodgson, J., Shrestha, T. B., Thapa, P.S., Moore, D., Wu, X., Ikenberry, M., Troyer, D.L., Wand, D., Hohn, K., Bossmann, S. H., “Carbon Dioxide Hydrogenation to Aromatic Hydrocarbons by Using an Iron/Iron Oxide Nanocatalyst ” Beilstein Journal of Nanotechnology.
2013
- Sukthankar, P., Gudlur, S., Avila, A. L., Whitaker, S. K., Katz, B. B., Hiromasa, Y., Gao, J., Thapa, P., Moore, D., Iwamoto, T., Chen, J. and Tomich, J. M. “Branched-Oligopeptide Forms Capsules with Lipid Vesicle-Like Characteristics ” Langmuir.
- Jin, X., Roy, D., Thapa, P. S., Subramaniam, B. and Chaudhari, R. V. “Atom Economical Aqueous-Phase Conversion (APC) of Biopolyols to Lactic Acid, Glycols, and Linear Alcohols Using Supported Metal Catalysts.” ACS Sustainable Chemistry & Engineering.
- Liu, J. W., Lu, R., Xu, G., Wu, J., Thapa, P., and Moore, D., “Development of Seedless Floating Growth Process in Solution for Synthesis of Crystalline ZnO Micro/Nanowire Arrays on Graphene: Towards High-Performance Nanohybrid Ultraviolet Photodetectors.” Adv. Func. Mater.
2012
- Wang, H. W., Shrestha, T. B., Seo, G. M., Basel, M. T., Dani, R. K., Seo, G. M., Balivada, S., Pyle, M., Prock, H., Koper, O. B., Thapa, P. S., Moore, D., Li, P., Chikan, V., Troyer, D. L. and Bossmann S. H.,“Magnetic –Fe/Fe3O4-Nanoparticle-Bound SN38 as Carboxylesterase-Cleavable Prodrug for the Delivery to Tumors Within Monocytes/Macrophages.” Beilstein J. Nanotechnology, 9.
- Shrestha, T. B., Seo, G. M., Basel, M. T., Kalita, M., Wang, H. W., Villanueva, D., Pyle, M., Balivada, S., Rachakatla, R. S., Shinogle, H., Thapa, P. S., Moore, D., Troyer, D. L. and Bossmann S. H.,“Stem Cell-Based Photodynamic Therapy.” Photochemical & Photobiological Sciences.
- Pandey, B., Thapa, P. S., Higgins, D. A., and Ito Takashi, “Formation of Self-Organized Nanoporous Anodic Oxide from Metallic Gallium.” Langmuir.
- Paneru, G., Thapa, P. S., McBride, S. P., Rann, A., Law, B. M. and Flanders, B. N, “Long Reach Cantileveres for Sub-Cellular Force Measurements.” Nanotechnology, 23.
2011
- Paneru, G., Thapa, P. S., McBride, S. P., Moore, D. S., Law, B. M. and Flanders, B. N. “Forces at Individual Pseudopod-Filament Adhesive Contacts.” Appl. Phys. Lett., 99.
2009
- Thapa, P. S., Ackerson, B.J., Grischkowsky, D. R. and Flanders, B. N. “Directional Growth of Metallic and Polymeric Nanowires.” Nanotechnology, 20.
- Thapa, P. S., Yu, D. J., Wicksted, J. P., Hadwiger, J. A., Barisci, J. N., Baughman, R. H. and Flanders, B. N. “Directional Growth of Conducting Polypyrrole and Polythiophene nanowires.” Appl. Phys. Lett., 94.
- Dale, E., Ganta, D., Stoian, R. I., Thapa, P., Yu, D.J., Flanders, B.N. and Rosenberger, A. T. “Spatially Localized Enhancement of Evanescent Coupling to Whispering-Gallery Modes at 1550 nm due to Surface Plasmon Resonances of Au Nanowire Fragments.” International Quantum Electronics Conference.
2007
- Su, A.; Tan, S., Thapa, P. S., Flanders, B.N. and Ford, W.T. “Highly Ordered Langmuir-Blodgett Films of Amphiphilic Poly (Propylene imine) Dendrimers.” J. Phys. Chem. C, 111(12) 4695-4701.